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In this study we show that p62 binds directly to LC3A and -B and other human Atg8 homologues such as GABARAP, GABARAPL1, and GABARAPL2 p62 slot Independently, p62 serves also as a shuttling protein for ubiquitinated substrates, using its PB1 domain This places p62 in a pivotal position where under

p62 slotscientifica Science ha identificato la proteina utile ai processi vitali delle cellule malate, la p62 Un passo avanti verso nuove cure

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